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Drinking and driving isn't only dangerous for the other person but additionally the driver and the guests of the car it self. You should keep from drinking and driving as there's a significantly increased threat of automobile accidents, damage to property and injury to people. Prevention is always better than cure. Therefore, drinking and driving should not get together in fact it's stupid. Large penalties can be impounded on the accused, like suspension of drivers license, fines, a period in confiscation and jail of car registration plates.  
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The following popper user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlDisplay Settings:AbstractThe following popper user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlSend to:
 
Mol Microbiol. 1989 Aug;3(8):995-1002.
 
The terminus of the Escherichia coli chromosome is flanked by several polar replication pause sites.
 
François V, Louarn J, Louarn JM.
 
Source
 
Centre de Biochimie et de Génétique Cellulaires du CNRS, Toulouse, France.
 
Abstract
 
Replication of two small 'constrained' regions of the Escherichia coli chromosome, one bordered by replication terminator T1 and the other by T2, displays normal velocity in the normal direction whereas it is much slower in the opposite direction (de Massy et al., 1987). The presence of multiple polar terminators has been investigated, using a bacteriophage lambda derivative which provides a replication origin movable to predetermined loci and inducible on demand. The amount of DNA made from this induced origin was determined by in vivo labelling and hybridization to probes of the surrounding region. A redundancy of terminator-like sequences, or pause sites, has been disclosed. So far, two polar pause sites, in the same orientation and separated by 50 or 80 kb, have been localized on each side of the terminus region. The results are discussed in relation to previously observations indicating that these regions are refractory to genomic inversions.
 
PMID: 2532703 [PubMed - indexed for MEDLINE]
 
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MeSH Terms, Substances
 
MeSH Terms
 
Bacteriophage lambda/genetics
 
Base Sequence
 
Chromosome Mapping
 
Chromosomes, Bacterial/metabolism*
 
DNA Replication*
 
Escherichia coli/genetics*
 
Immunoblotting
 
Sequence Homology, Nucleic Acid
 
Terminator Regions, Genetic
 
Thymidine/metabolism
 
Time Factors
 
Substances
 
Thymidine
 
The following toggler user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface control
 
LinkOut - more resources
 
Supplemental Content
 
  
Save items
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There are thousands of people getting hurt or dying as a result of drinking and driving annually. About 20% of the traffic fatalities all around the world take place as a result of dui. We, like responsible citizens, must comprehend the ill ramifications of dui and keep from doing it. DUI or Drinking under the Influence of Intoxicants may cause problems in the present and in the future. Law enforcement must hold random checks on drunk drivers, particularly at night to reduce the risk and get the offenders. A breath analyzer test may be the most frequent test used to catch the offenders.  
The following setswitch user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlAdd to Favorites
 
View more options
 
Related citations in PubMed
 
Constraints in chromosomal inversions in Escherichia coli are not explained by replication pausing at inverted terminator-like sequences.
 
[Mol Microbiol. 1990]
 
The terminus region of the Escherichia coli chromosome contains two separate loci that exhibit polar inhibition of replication.
 
[Proc Natl Acad Sci U S A. 1987]
 
Inhibition of replication forks exiting the terminus region of the Escherichia coli chromosome occurs at two loci separated by 5 min.
 
[Proc Natl Acad Sci U S A. 1987]
 
Review Termination of DNA replication of bacterial and plasmid chromosomes.
 
[Mol Microbiol. 1999]
 
Review Mechanisms of polar arrest of a replication fork.
 
[Mol Microbiol. 2009]
 
See reviews...
 
See all...
 
Cited by 10 PubMed Central articles
 
Review Replication termination in Escherichia coli: structure and antihelicase activity of the Tus-Ter complex.
 
[Microbiol Mol Biol Rev. 2005]
 
Review Linkage map of Escherichia coli K-12, edition 10: the traditional map.
 
[Microbiol Mol Biol Rev. 1998]
 
Search for additional replication terminators in the Bacillus subtilis 168 chromosome.
 
[J Bacteriol. 1997]
 
See all...
 
Related information
 
Related Citations
 
Compound
 
Compound (MeSH Keyword)
 
Substance
 
Substance (MeSH Keyword)
 
Cited in PMC
 
Recent activity
 
Clear Turn Off
 
The terminus of the Escherichia coli chromosome is flanked by several polar repl...
 
PubMed
 
See more...
 
You are here: NCBI > Literature > PubMedWrite to the Help Desk
 
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GETTING STARTED
 
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Data & Software
 
DNA & RNA
 
Domains & Structures
 
Genes & Expression
 
Genetics & Medicine
 
Genomes & Maps
 
Homology
 
Literature
 
Proteins
 
Sequence Analysis
 
Taxonomy
 
Training & Tutorials
 
Variation
 
POPULAR
 
PubMed
 
Nucleotide
 
BLAST
 
PubMed Central
 
Gene
 
Bookshelf
 
Protein
 
OMIM
 
Genome
 
SNP
 
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FEATURED
 
Genetic Testing Registry
 
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Sequence Read Archive
 
NCBI INFORMATION
 
About NCBI
 
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NCBI on Facebook
 
NCBI on Twitter
 
NCBI on YouTube
 
NLM NIH DHHS USA.gov
 
Copyright | Disclaimer | Privacy | Browsers | Accessibility | Contact
 
National Center for Biotechnology Information, U.S. National Library of Medicine
 
8600 Rockville Pike, Bethesda MD, 20894 USA The following menu user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface control
 
NCBI
 
Skip to main content
 
Skip to navigation
 
Resources
 
How To
 
About NCBI Accesskeys
 
Sign in to NCBI
 
PubMed
 
US National Library of Medicine National Institutes of Health
 
Search termSearch database
 
The following autocomplete user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlSearch
 
AdvancedHelp
 
Result Filters
 
The following popper user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlDisplay Settings:AbstractThe following popper user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlSend to:
 
Mol Microbiol. 1989 Aug;3(8):995-1002.
 
The terminus of the Escherichia coli chromosome is flanked by several polar replication pause sites.
 
François V, Louarn J, Louarn JM.
 
Source
 
Centre de Biochimie et de Génétique Cellulaires du CNRS, Toulouse, France.
 
Abstract
 
Replication of two small 'constrained' regions of the Escherichia coli chromosome, one bordered by replication terminator T1 and the other by T2, displays normal velocity in the normal direction whereas it is much slower in the opposite direction (de Massy et al., 1987). The presence of multiple polar terminators has been investigated, using a bacteriophage lambda derivative which provides a replication origin movable to predetermined loci and inducible on demand. The amount of DNA made from this induced origin was determined by in vivo labelling and hybridization to probes of the surrounding region. A redundancy of terminator-like sequences, or pause sites, has been disclosed. So far, two polar pause sites, in the same orientation and separated by 50 or 80 kb, have been localized on each side of the terminus region. The results are discussed in relation to previously observations indicating that these regions are refractory to genomic inversions.
 
PMID: 2532703 [PubMed - indexed for MEDLINE]
 
The following toggler user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface control
 
MeSH Terms, Substances
 
MeSH Terms
 
Bacteriophage lambda/genetics
 
Base Sequence
 
Chromosome Mapping
 
Chromosomes, Bacterial/metabolism*
 
DNA Replication*
 
Escherichia coli/genetics*
 
Immunoblotting
 
Sequence Homology, Nucleic Acid
 
Terminator Regions, Genetic
 
Thymidine/metabolism
 
Time Factors
 
Substances
 
Thymidine
 
The following toggler user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface control
 
LinkOut - more resources
 
Supplemental Content
 
  
Save items
+
Also, studies show that half of the offenders caught weren't beneath the influence of alcohol but other banned substances like drugs. Parents must warn their children against drunk driving and show their very own daily lives with their children by example. They should make their kids understand the importance of being a responsible person. And, they should do nothing to bring any injury or any injury to people including something as reckless as dui.  
The following setswitch user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.Destroy user interface controlAdd to Favorites
+
 
View more options
+
There are specific measures which can be applied to control drunk driving. Regular checks for drunk drivers traveling may be carried out by what the law states. Offenders should be severely punished in the form of levying heavy fines and penalties. Permits of typical offenders should be suspended or terminated. Treatment programs should really be conducted for those people who cant kiss the practice farewell. Adequate information should be provided by every state on the bad effects of DUI during the time of the owners assessments.  
Related citations in PubMed
+
 
Constraints in chromosomal inversions in Escherichia coli are not explained by replication pausing at inverted terminator-like sequences.
+
Many cars will have technological devices available like alarm systems just in case the driver inside falls asleep. So that the car brakes automatically if it's about to crash with another thing in the front or the back they will soon be fitted with anti impact units.  
[Mol Microbiol. 1990]
+
 
The terminus region of the Escherichia coli chromosome contains two separate loci that exhibit polar inhibition of replication.
+
Remember by being truly a responsible person you set a good example to other people as well. Don't unnecessarily force the others to drink at your parties. See to it that the party gets over well within time so that people can leave early. And provide alternate means of transport for those that drink.  
[Proc Natl Acad Sci U S A. 1987]
+
 
Inhibition of replication forks exiting the terminus region of the Escherichia coli chromosome occurs at two loci separated by 5 min.
+
If you are arrested for DUI, then hiring a DUI lawyer proves to function as best choice. Operating underneath the influence can have serious consequences on you if you are involved in an auto accident. Consequences may be faced by you like jail or prison, penalties or fines, vehicle impoundment, etc. The DUI lawyer is familiar with the intricacies and procedures involved with DUI costs and are your absolute best bet if you find yourself in such a problem. [http://www.legal-eagles.com/ child support lawyer]
[Proc Natl Acad Sci U S A. 1987]
 
Review Termination of DNA replication of bacterial and plasmid chromosomes.
 
[Mol Microbiol. 1999]
 
Review Mechanisms of polar arrest of a replication fork.
 
[Mol Microbiol. 2009]
 
See reviews...
 
See all...
 
Cited by 10 PubMed Central articles
 
Review Replication termination in Escherichia coli: structure and antihelicase activity of the Tus-Ter complex.
 
[Microbiol Mol Biol Rev. 2005]
 
Review Linkage map of Escherichia coli K-12, edition 10: the traditional map.
 
[Microbiol Mol Biol Rev. 1998]
 
Search for additional replication terminators in the Bacillus subtilis 168 chromosome.
 
[J Bacteriol. 1997]
 
See all...
 
Related information
 
Related Citations
 
Compound
 
Compound (MeSH Keyword)
 
Substance
 
Substance (MeSH Keyword)
 
Cited in PMC
 
Recent activity
 
Clear Turn Off
 
The terminus of the Escherichia coli chromosome is flanked by several polar repl...
 
PubMed
 
See more...
 
You are here: NCBI > Literature > PubMedWrite to the Help Desk
 
Simple NCBI Directory
 
GETTING STARTED
 
NCBI Education
 
NCBI Help Manual
 
NCBI Handbook
 
Training & Tutorials
 
RESOURCES
 
Chemicals & Bioassays
 
Data & Software
 
DNA & RNA
 
Domains & Structures
 
Genes & Expression
 
Genetics & Medicine
 
Genomes & Maps
 
Homology
 
Literature
 
Proteins
 
Sequence Analysis
 
Taxonomy
 
Training & Tutorials
 
Variation
 
POPULAR
 
PubMed
 
Nucleotide
 
BLAST
 
PubMed Central
 
Gene
 
Bookshelf
 
Protein
 
OMIM
 
Genome
 
SNP
 
Structure
 
FEATURED
 
Genetic Testing Registry
 
PubMed Health
 
GenBank
 
Reference Sequences
 
Map Viewer
 
Human Genome
 
Mouse Genome
 
Influenza Virus
 
Primer-BLAST
 
Sequence Read Archive
 
NCBI INFORMATION
 
About NCBI
 
Research at NCBI
 
NCBI Newsletter
 
NCBI FTP Site
 
NCBI on Facebook
 
NCBI on Twitter
 
NCBI on YouTube
 
NLM NIH DHHS USA.gov
 
Copyright | Disclaimer | Privacy | Browsers | Accessibility | Contact
 
National Center for Biotechnology Information, U.S. National Library of Medicine
 
8600 Rockville Pike, Bethesda MD, 20894 USA
 

Revision as of 17:26, 18 March 2013

Drinking and driving isn't only dangerous for the other person but additionally the driver and the guests of the car it self. You should keep from drinking and driving as there's a significantly increased threat of automobile accidents, damage to property and injury to people. Prevention is always better than cure. Therefore, drinking and driving should not get together in fact it's stupid. Large penalties can be impounded on the accused, like suspension of drivers license, fines, a period in confiscation and jail of car registration plates.

There are thousands of people getting hurt or dying as a result of drinking and driving annually. About 20% of the traffic fatalities all around the world take place as a result of dui. We, like responsible citizens, must comprehend the ill ramifications of dui and keep from doing it. DUI or Drinking under the Influence of Intoxicants may cause problems in the present and in the future. Law enforcement must hold random checks on drunk drivers, particularly at night to reduce the risk and get the offenders. A breath analyzer test may be the most frequent test used to catch the offenders.

Also, studies show that half of the offenders caught weren't beneath the influence of alcohol but other banned substances like drugs. Parents must warn their children against drunk driving and show their very own daily lives with their children by example. They should make their kids understand the importance of being a responsible person. And, they should do nothing to bring any injury or any injury to people including something as reckless as dui.

There are specific measures which can be applied to control drunk driving. Regular checks for drunk drivers traveling may be carried out by what the law states. Offenders should be severely punished in the form of levying heavy fines and penalties. Permits of typical offenders should be suspended or terminated. Treatment programs should really be conducted for those people who cant kiss the practice farewell. Adequate information should be provided by every state on the bad effects of DUI during the time of the owners assessments.

Many cars will have technological devices available like alarm systems just in case the driver inside falls asleep. So that the car brakes automatically if it's about to crash with another thing in the front or the back they will soon be fitted with anti impact units.

Remember by being truly a responsible person you set a good example to other people as well. Don't unnecessarily force the others to drink at your parties. See to it that the party gets over well within time so that people can leave early. And provide alternate means of transport for those that drink.

If you are arrested for DUI, then hiring a DUI lawyer proves to function as best choice. Operating underneath the influence can have serious consequences on you if you are involved in an auto accident. Consequences may be faced by you like jail or prison, penalties or fines, vehicle impoundment, etc. The DUI lawyer is familiar with the intricacies and procedures involved with DUI costs and are your absolute best bet if you find yourself in such a problem. child support lawyer